1. Standardizing Animal Managemnet and Use

The Company has established Institutional Animal Care and Use Committee (IACUC) consisting of veterinarians, experts with rich experience in animal testing, non-animal test participants of the group, and public representatives, responsible for supervising the management and use of animals. During the reporting period, we revised the IACUC Approval Procedure for Animal Management and Use to further optimize and improve the animal management and use process. For all animal experiments, the subject responsible person needs to submit an approval form before the experiment starts. IACUC members need to strictly review the approval form submitted by the subject responsible person, and the test can only be conducted after passing the review. When significant changes affecting animal welfare are involved in the test process, the subject responsible person needs to fill in the record form and submit it to the IACUC management for review and approval. IACUC inspects experimental animal facilities and animal feeding and management every six months. After the launch of each animal testing topic, IACUC members and/or QA will irregularly supervise and inspect the animal welfare during the breeding and use of experimental animals. If any issues that violate animal welfare requirements are found during the inspection, they will adopt methods such as evaluation, necessary investigation, or transfer to relevant departments to make final conclusions and handling. Currently, the handling methods for violations of animal welfare include oral warning, written warning, track and inspect, temporarily or permanently disqualify relevant personnel from contacting animals, report to the person in charge, etc.

To ensure that all personnel related to experimental animals can understand the importance of animal welfare, we provide comprehensive and systematic animal welfare training for new employees when they enter the workforce. In our daily work, we also provide regular training to employees to ensure animal welfare.

2. Animal Welfare Care

We are committed to providing good conditions for animals to guarantee the welfare of experimental animals, including: comfortable accommodation and adequate entertainment time, necessary social activities, health monitoring and care, etc. The specific welfare protection measures are as follows: