One of the services we provide at CTI is the preclinical evaluation of drugs. To verify the safety and efficacy of drugs, and figure out their absorption, distribution, metabolism and excretion process in an organism, we are required to perform animal testing before the marketing of new drugs. This has been permitted by governments around the world and is widely deemed mandatory. Though as we all know, technologies such as computer modeling, cell culture, and organs-on-chips are extensively applied to biomedical research, they remain unable to completely imitate the complexity of the human organism. In other words, the role of animal experiments in showing how a new drug reacts in an intact living body cannot be replaced yet.
We are aware more than ever that the deep concern for laboratory animals is not only the right choice to guarantee reliable test results, but also embodies the respect and awe of life. Therefore, we promise to care and respect all experiment animals and treat them in a humane way.
Our Performance in 2020
Regulated Use of Animals
We have developed explicit operating procedures to specify: the space of laboratory animal cages and the number of animals each cage may hold; the health monitoring and care of laboratory animals; the environmental enrichment for experimental animals and their euthanasia. We make sure all employees who work with laboratory animals have received extensive training – new recruits are trained on animal welfare at the time of onboarding; regular training is organized for employees in daily work, to enhance their awareness of animal welfare, and ensure they choose right management and care methods where necessary.
Animal Welfare and Care
In order to improve the quality of life and welfare of laboratory animals, we provide them with a comfortable residence and sufficient entertainment time, necessary social activities, health monitoring and care. We have experimental animal monuments, and we pay tribute to the animals and present flowers at least once a year.
Supervision over Animal Management and Use
We have established an Institutional Animal Care and Use Committee (IACUC) to supervise the management and use of animals. The committee is joined by veterinarians, experts with extensive experience in animal testing, Group staff not engaged in animal testing, and public representatives. IACUC takes charge of the following three tasks: inspecting the facilities and feeding of experimental animals every six months; supervising animal welfare during the feeding and use of experimental animals; and reviewing animal testing proposals and the records of animal management and use. In case of any issue found in violation of animal welfare provisions, IACUC is required to make assessment, launch necessary investigation or transfer the case to relevant departments, among other approaches, and then make a final conclusion and impose a penalty. Applicable penalties include but are not limited to verbal warnings, written warnings, follow-up inspections, and temporary or permanent cancellation of qualification for contact with animals, reporting to supervisors, etc.